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Student
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Project topic
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Supervisor(s)
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Naomi Thorne
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Investigating mitochondrial-derived vesicles and their relationship
to Parkinson's pathology.
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David Tumbarello, Roxana Carare
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Michael Price
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Light-mediated switching of circadian pacemaker function across the
neural clock circuit of Drosophila
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Herman Wijnen, Mariana Vargos-Caballero
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Christina Georgiadou
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The role of FcRIIb in Parkinson's
Disease
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Jessica Teeling, Phil Williamson, Herman Wijnen
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Ellie Seaby
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The integration of clinical samples with 300,000 reference exomes and
genomes for health and disease
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Sarah Ennis, Heidi Rehm
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Pooja Khurana
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The physiological and cellular mechanisms underlying adverse
developmental programming.
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Tom Fleming
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Jessica Bampton
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SOS for plant stress: single oxygen signalling pathways mediating
stress acclimation in plants
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Matthew Terry, Haruko Okamoto
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Steve John
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Chemical probes for precise dissection of the Wnt
signalling pathway
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Matthias Baud, Rob Ewing, Graham Packham, Paul Skipp
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James Coates
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A platform for monitoring skin health
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Andy Chipperfield, Geraldine Clough, John Tudor
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Guilia Lioi
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Developing a clinical measurement of depth of anaesthesia using brain
connectivity measures.
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Steven Bell, David Smith, David Simpson
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Monica Guerro-Carrasco
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Understanding the role of early-life inflammation on the incidence of
Alzheimer's disease
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Diego Gomez-Nicola, Mariana Vargas-Caballero
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Samah Zarroug
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Associative learning in C.elegans.
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Lindy Holden-Dye, Vincent O'Connor, Steven Glautier
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Bradleigh Whitton
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The investigation of the role of vacuolar
type proton pump ATPases (V-ATPase) in prostate cancer.
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Haruko Okamoto, Simon Crabb
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Giedo Elamin
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Microparticles involvement in the dynamics of thrombus formation and
dissolution.
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Nicola Englyst, John Holloway, Judith Holloway
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Sebastien Pollet
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Cortical activity changes among stroke patients following robotic
upper limb rehabilitation as measured by EEG during reach movements.
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Jane Burridge, Bernard Conway, Brigitte Lavoie
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Gaia Andreoletti
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Interrogation of physiological pathways in paediatric inflammatory
bowel disease using exome analysis.
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Sarah Ennis, Andrew Collins, Mark Beattie
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Charlotte Hill
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Role of autophagy in the regulation of epithelial-mesenchymal
transition (EMT), invasion and metastasis in RAS mutated tumour
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Yihua Wang
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Helena Rawsthorne
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Modelling decision making in C.elegans: a platform to investigate major
psychiatric disease
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Lindy Holden Dye, James Dillon
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Maria Fankhaenel
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Unravelling the genetic and developmental mechanisms of asymmetric
cell division in mammary stem cells
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Salah Elias, Keith Jones
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Rebecca Carter
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Control of Zn homeostasis and the contribution to plant physiology
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Lorraine Williams
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Stephanie Robinson
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Lymphatic Networks & infiltrating cells in lung: Modelling and
quantitative analysis of structural relationships in real lung samples
imaged by micro computed tomography (µCT) and immunohistochemistry
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Peter Lackie, Tina Roose
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Evelin Szalai
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Physiological role of protein phosphatase 1 during chromosome
segregation
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Marcin Przewloka, Paul Skipp
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Devon Lewis
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Interfaces with the nervous system for the control of neuroprostheses: bioinspired approaches using an insect
model.
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Phil Newland, David Simpson, Liudi Jiang
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Jessica Bampton
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SOS for plant stress: single oxygen signalling pathways mediating
stress acclimation in plants
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Matthew Terry, Haruko Okamoto
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Dianne Lopez
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What is the limiting step in pathogenic tau transmission along
neuronal networks?
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Katrin Deinhardt, Mark Coldwell, Jonathan West
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Hannah Warming
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Recovery of neuronal function and memory in a mouse model of
haemorrhagic stroke
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Mariana Vargas-Cabalerro, Ian Galea, Diederik Bulters
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Lauren McNicholas
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Ups and downs of NMDAR phosphorylation by Fyn kinase: relevance for
synaptic function in AD
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Katrin Deinhardt, Mariana Vargas-Caballero
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Dawn Cooper
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Interactions between airborne triggers of asthma
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Matthew Loxham, Emily Swindle, Damon Teagle
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Ben Bachelor
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How Aβ42 influences Tau phenotypes in a
Drosophila model
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Amrit Mudher
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Lloyd Steele-Nicholson
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Enhancing integrin-mediated neurite outgrowth and repair
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David Tumbarello, Melissa Andrews
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Laura Cooke
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Mechanisms of placental vitamin D handling and prenatal programming
of adult obesity
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Jane Cleal, Jaswinder Sethi, Pam Mahon, Nicholas Harvey
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Jacob Trend
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Does common aetiology between Alzheimer's disease and osteoporosis
exist?
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Claire Clarkin, Katrin Deinhardt, Schneider
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Juan Nunez
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Examining 3D blood vessel structures in bone during development,
adulthood and disease using Synchrotron and Laboratory µCT analysis
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Claire Clarkin, Ian Sinclair
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Charles Hurdle
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Multi-functional environmental sensing by CRYPTOCHROME in a
Drosophila model
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Herman Wijnen, Chris Jackson
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Monika Kudelska
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Generation of a screening platform for the Cys-loop
superfamily of ligand gated ion channels.
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Declan Doyle, Lindy Holden-Dye
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Emilia Assar
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Defining the cellular and molecular function of endocytic adaptors in
membrane trafficking and cellular signalling
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David Tumbarello, Katrin Deinhardt
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Connor Maltby
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Regulation of neuronal mRNA transport and protein synthesis by
G-quadruplexes.
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Mark Coldwell, Katrin Deinhardt
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Tania Garcia Becarra
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The Physiological role of G protein coupled receptor type G proteins
(CTGs) in plants in response to stress
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Lorraine Williams, Matthew Terry
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Jemma Paterson
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Not just skin deep: circulating lipids in a "localised"
disease.
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Tim Millar
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Eleni Palaiologou
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Three dimensional imaging of placental
perivascular cell populations and their function.
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Rohan Lewis, Jane Cleal, Christopher Torrens
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Adam Dorey
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Are GTGs a new class of anion channels regulating pH in the
endomembrane system?
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Lorraine Williams, Ita O'Kelly, Matthew Terry
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Kerry Day (nee Gove)
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Physiological measurements of small airways in COPD relates to
functional changes seen in imaging and structural changes in MicroCT and can predict early disease pathology
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Tom Wilkinson, Peter Howarth, Bruce Thompson
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Andrew Hutton
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Inflammation in the Airways: an ex vivo model
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Jane Warner, Chris Pickard
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Prutha Patel
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Neuro Traffic: Oriented neuronal networks for investigating
mechanisms of tau propagation.
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Katrin Deinhardt, Jonathan West
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Claire Simner
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Does maternal vitamin D regulate placental amino acid transport and
subsequent fetal growth?
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Jane Cleal, Nicolas Harvey, Karen Lillycrop
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Megan Sealey
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How do aging processes contribute to Alzheimer's disease?
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Amrit Mudher, Delphine Boche
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Nicolas Dalliere
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Neuropeptide-dependent plasticity of neuronal circuits that integrate
feeding behaviour.
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Lindy Holden-Dye, Vincent O'Connor
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Emily Farthing
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Dissecting pathways involved in manganese homeostasis in higher
plants.
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Lorraine Williams
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Mel Jannaway
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Modulators of airway and vascular smooth muscle contraction.
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Tony Sampson, Jane Warner, Christopher Torrens
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Przemyslaw Ociepa
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Characterising the function of the rhamnogalacturonan II component of
pectin during plant development
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Alan Marchant
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Lisa Jones
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The impact of reduced pregnancy vitamin D status on offspring muscle
development
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Lucy Green, Kirstin Poore, Jane Cleal
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Chrysia Pegasiou
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Translating knowledge from mouse to human: How does amyloid beta
affect synaptic function?
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Maria Vargas-Caballero, Hugh Perry
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Miguel Moreno
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Control of Drosophila circadian behaviour by the RH01-signalling
pathway
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Herman Wijnen
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Sophia Sander
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Role of microRNAs in the physiological regulation of human stem
cells.
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Franchesca Houghton, Tilman Sanchez-Elsner
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Alison Hill
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Role of mechanical forces in the pathophysiology of asthma.
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Christopher Grainge, Emily Swindle, Donna Davies
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Alex Collcutt
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Role of neuroinflammation in Tau pathology
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Ayodeji Asuni, Jessica Teeling, Amrit Mudher
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Alison Caldwell
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Investigation of the molecular mechanisms behind immune escape and
recognition of contagious cancers.
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Hannah Siddle, Tim Elliott
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Charlene Sibbons
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Epigenetic regulation of n-3 polyunsaturated fatty acid synthesis.
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Graham Burdge, Karen Lillycrop, Barbara
Fielding, Margot Umpleby
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Christine Reitmeyer
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Does diesel pollution impair learning and memory in the honey bee?
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Tracey Newman, Robbie Girling
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James Schofield
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Mechanisms of generation and functional significance of novel
isoforms of the two-pore potassium channel family.
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Mark Coldwell, Ita O'Kelly
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Charlotte Lawrence
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Small molecule inhibitors of the tumour hypoxia response network.
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Ali Tavassoli
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Jessica Rajaram
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Role of the peptides of the renin-angiotensin system in lung
physiology
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Jane Warner, Allison-Lyn Andrews, Christopher Torrens
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Nola Pickard (neé Adeosun)
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Cardioprotection mediated through green tea;
synthesis and biological evaluation of modified epicatechin and
epicatechin-3-gallate
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Paul Townsend, Ali Tavassoli
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Katherine Stubbs
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How does Wlds mediate protection in a
Drosophila model of tauopathies?
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Amritpal Mudher, Hugh Perry
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Matthew Davies
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Neurodegeneration associated stress responses in an in vivo model
of experimentally induced prion disease
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Vincent O'Connor, Hugh Perry
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Nancy Wong
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The physiological function of the GTG/GPHRs a highly conserved family
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Neil Smyth, Lorraine Williams, Matthew Terry
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Alison Yeomans (neé Donlevy)
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Using chemical probes to investigate redox regulation of of angiogenesis
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Graham Packham, Mark Coldwell
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Emma Lofthouse (neé Field)
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Transport, transfer and regulation: three key questions about
placental transport
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Rohan Lewis, Kirstin Poore, Mark Hanson
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Kirstin Williamson
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How does the immune system interact with the increasing vulnerability
of the ageing nervous system?
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Amrit Mudher, Joel Parker, Lex Kraaijevald
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Sarah Louise Williams
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Role of the two-pore domain potassium channel (K_2P 9.1) in colon
cancer
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Ita O'Kelly, Andrew Bateman
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Raffaella Petruzelli
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Hypoxic regulation of human embryonic stem cell maintenance
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Francesca Houghton
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Louise Fairless
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Physiological aspects of roosting behaviour in vespertilionid bats.
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Felix Eigenbrod, Patrick Doncaste,r
Lex Kraaijeveld, Phil Newland
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Rebecca Stead
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Role of the Mnks (protein kinases) in the
regulation of protein synthesis
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Chris Proud
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Sam Collins
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The role of hypoxia and DNA mismatch repair in neuroblastoma
multicellular spheroid formation
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Jeremy Webb, Jeremy Blades
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Aneta Rybka
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The physiological and molecular understanding of the role of STAT and
HDAC proteins in cardiac cell hypertrophy
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Paul Townsend
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Pia Keskivali
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Acute statin treatment in a model of maternally induced endothelial
dysfunction
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Christopher Torrens, Nick Curzen, Geraldine
Clough
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Helga Groll
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The role of peripheral and central processing of olfactory
information in a parasitoid's brain.
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Guy Poppy, Phil Newland
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Laura Roncorroni
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Binding partners for hK2P15.1, a background potassium channel
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Ita O'Kelly, David Wilson
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James Atherton
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Do endothelial microparticles predict defects in coagulation function
after cardiac surgery
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Nicola Englyst, Geraldine Clough, David Smith, Judith Holloway
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Angela Cheung
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Cell culture: into the third dimension
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Phil Newland, Liam Gray
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Priscilla Day
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Transport across the human placenta
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Rohan Lewis
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Ayse Ismail
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Interactions between human embryonic stem cells and fetal femur-derived cell populations
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Richard Oreffo
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Olly Dewhirst
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Effectiveness of a Volterra model of the locust's hind leg reflex
control loop in predicting its response to physiological input signals
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Phil Newland, David Simpson, Neil White
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Nik Rogers
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Determining the membrane aqueous border of a voltage gated potassium
channel
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Malcolm East, Tony Lee
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Neil Roberts
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Human pancreas development the role and regulation of SOX9
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Karen Piper-Hanley, Neil Hanley
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Umar Sajjid
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Oxidative stress in Huntington's disease
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Andreas Wyttenbach, Vincent O'Connor
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Catherine Forristal
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Hypoxic regulation of human embryonic stem cells
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Francesca Houghton
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Shmma Quraishe
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Expression of the small heat shock protein chaperone family in the
mouse CNS
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Vincent O'Connor, Andreas Wyttenbach
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Simone Holley
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Defects in executive function are associated with sleep disturbance
in children of 6-12 years
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Jim Stephenson
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Sylvia Gaspar Pereira
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The role of NF-kB1 in the heart
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Fiona Oakley, Paul Townsend
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Rebecca Holloway
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The role of elastase as an inflammatory stimulus in chronic
obstructive pulmonary disease (COPD)
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Jane Warner, Richard Foreman
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Daniel Asby
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Normal human sexual differentiation in females is influenced by
androgens
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Neil Hanley
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Cally Gill
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Proteomic analysis of interstitial fluid for novel markers of the
early response to injury
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Geraldine Clough, David O'Connor
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Paula Costello
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The effect of maternal nutrition and body composition on the
structure and function of skeletal muscle in the offspring.
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Lucy Green, Mark Hanson
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Mohinder Pal
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Protein mis-folding and human disease.
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Jon Cooper
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Michael James Blackney
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Characterising Drosophila extracellular superoxide dismutase
gene
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David Shepherd, Joel Parker
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Fiona Oakley
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Histidine stimulated trace metal uptake into human erythrocytes, HEL
cells and HEL total RNA injected Xenopus laevis oocytes.
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Niall Horn, Alan Thomas
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Sarah Young
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The effect of diet on food preference and life history traits in
Drosophila melanogaster.
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David Shepherd, Philip Newland
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Neil Ravenhill
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The biochemistry of serpin secretion: an investigation into the
effects of mutant and corrective variants.
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Richard Foreman
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Cassie Richardson
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Awareness in Ageing.
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Alexandra M. Hogan,Romola
Bucks
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